FOXO3 promotes longevity by activating genes involved in stress resilience, antioxidant defense, DNA repair, tumor cell killing, and preventing protein aggregation.

“I mean Fox o3 is a transcription factor it regulates whole host of genes many of which have to do with DNA repair at ah Fuji stem cell function production of antioxidants and anti-inflammatory pathway so it's a lot of really good stuff you want active all the time”

“the reason foxo3 is associated with longevity is because it turns on a whole host of genes that make you more resilient to stress it turns on antioxidant genes it turns on genes that repair DNA damage it turns on genes that kill tumor cells and it turns on genes that make sure proteins don't Aggregate and Clump inside of your cells”