Bryan Johnson· Author
While VO2 Max indicates systemic capacity of oxygen utilization and cardiorespiratory fitness, SmO2 shows how adaptive your muscles are to stress and strain.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
While VO2 Max indicates systemic capacity of oxygen utilization and cardiorespiratory fitness, SmO2 shows how adaptive your muscles are to stress and strain.
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