Andrew Huberman· PhD
The NIH now has mandatory guidelines for including both sexes in research studies (unless the specific topic of the study is sex specific of course).
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The NIH now has mandatory guidelines for including both sexes in research studies (unless the specific topic of the study is sex specific of course).
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Actually recently, I guess it was about five years ago, the national institutes of health made it a mandate that all studies use sex as a biological variable, and actually explore both sexes of mice, both sexes of humans when doing any kind of study because there was a bias towards only using male animals or male subjects prior to that time.
It's now required that both male and female rodents and humans be studied in a given study unless the study is specifically geared toward understanding that only exists in one or the other population
yes and now it's required no Grant will get funded without sex as a biological variable and here I'm I'm by the way folks this is sex biological sex the noun not sex the verb both are super interesting obviously but — when we say sex as a biological variable meaning even even if it's a study on mice where did that start though that didn't start that long ago
I think there is a growing trend, at least among NIH-funded grants to require that as they refer to it in the grants of biological sex as a variable.
the NIH I know this because I'm on study section which is just a bunch of people who record who review grants is that every Grant now has to include sex as a biological variable it's hard to get away with um or rather I should say it the way it should be said which is people are required and should want to look at these phenomena in male and female mice yes especially if there are differences
So believe it or not, it was all done on male mice for large largely male uh done. That changed um now with changes in the way that you know um science is being done and funded. This is this issue has become prominent again.