Andrew Huberman· PhD
Dihydrotestosterone binds to the androgen receptor at five times the affinity of testosterone, so it is the most powerful androgen in humans
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Dihydrotestosterone binds to the androgen receptor at five times the affinity of testosterone, so it is the most powerful androgen in humans
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I think that DHT is something like two to five times more potent. So, and I just >> I thought it was even more than that. >> It could be more. But what this means is that it binds the receptor more tightly and it stays on for longer, which means that it um produces more of whatever the protein is that it's um upregulating