Whole genome sequencing is increasingly favored over whole exome sequencing as sequencing costs decrease and understanding of non-coding regions improves.

“it certainly was the case that a few years ago not that long ago it was so expensive to sequence a genome that we rarely did it it was really just cost prohibitive the exome was a really good shortcut because we didn't know what a lot of the other information meant anyway”

“increasingly we have a better sense of what the non-coding regions do uh we have better ability to interpret and recognize genetic Varian and so I would say as the sequencing costs have been coming down there's more of a shift to going to genomes rather than exomes”

“increasingly we have a better sense of what the non-coding regions do um we have better ability to interpret and recognize genetic Varian and so I would say as the sequencing costs have been coming down there's more of a shift to going to genomes rather than exomes”