Peter Attia· MD
so one of them is what's the strength of the association period so if if I knew nothing else the um was the asthma the 289 Celiac Celiac so the fact that that had such a strong Hazard ratio that a hazard ratio of 2.9 versus the others that are like 1.2 right you would say well just on the basis of strength of Association that one's more likely to be causal you then stated another factor which was reproducibility there's another study that's done the same analysis and it's coming up with the same answers so that makes it a little more likely to be causal and you talked about the dose effect even within the association like for example all of this was sort of figured out during the kind of smoking chalera epidemics when people were trying to understand causality and then you'd say well if smoking is causally related to lung cancer then theoretically my correlations should get stronger and stronger the more cigarettes you smoked if that's not the case it becomes very hard to make the case that smoking is causing lung cancer so you're saying that there was a dose effect the more antibiotics you took the more strongly you were having these associations yeah and this is the uh first formal study I've seen like this on an epidemiologic basis that that fits a hypothesis that to me makes sense