Andrew Huberman· PhD
we found in flies that social isolation increases the level of tachykinin in the brain, and if we shut that gene down, it prevents the isolation from increasing aggression.
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
we found in flies that social isolation increases the level of tachykinin in the brain, and if we shut that gene down, it prevents the isolation from increasing aggression.
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in flies, just like in people and practically any other social animal that shows aggression, social isolation increases aggressiveness.
So social isolation clearly drives powerful neurochemical and neuro biological changes, I really hope that Tachykinin-I and II, those are the main ones in humans? - Yeah, yeah. - Will be explored in more detail.
found, indeed, that one of the tachykinins, Drosophila tachykinin, those neurons when you activate them strongly promote aggression, and it depends on the release of tachykinin.
Now the interesting thing is that in flies just like in people and practically any other social animal that shows aggression, social isolation increases aggressiveness.
And indeed we found in flies that social isolation increases the level of tachikinan in the brain. And if we shut that gene down, it prevents the isolation from increasing aggression.