SAMe administration can rescue the effects of methionine restriction on the TOR pathway.

“it's the muscle meat that's rich in methane and that's where things are starting to go wrong it's okay as plant-based animal-based whatever doesn't matter whoever you are if you end up having this elevated ratio of methane into these other aminos there's some pretty clear evidence now well i shouldn't say clear it's in rodent models now but you're starting to see like methionine and how it turns into what's called you know esodinicil methionine which sam which ultimately goes to samtor which elevates mtor inhibits autophagy and essentially is stopping some of the recycling process in the beginning in the first place”