Antagonistic relationships, like the flexor-extensor muscle pairs and hunger-satiety circuits, are a consistent theme in brain function.

“Across neuroscience we see this pushpull right a flexor muscle like the bicep when it flexes the tricep relaxes. When the tricep flexes, the the bicep relaxes these antagonistic relationships. You see this in the hunger circuit. I mentioned one earlier. Like hunger and feeling full are they're like a pushpull. They're like a seessaw.”