POMC neurons in the hypothalamus influence hunger, appetite suppression, blood sugar regulation, and chewing.

“So the small collection of neurons in the hypothalamus to a number of different things related to sex behavior, aggression, mediating the temperature of your body, et cetera, but also appetite and suppressing appetite. And within the hypothalamus, there's a compact collection of these little neurons, which we referred to as the POMC, P-O-M-C neurons. And the name comes from the fact that they express certain peptides. And we won't get into that now, but the POMC neurons have a profound impact on whether or not you feel hungry or whether or not you do not feel hungry, whether or not your appetite is suppressed.”