Lactate produced during vigorous exercise acts as a signaling molecule that communicates with the brain to increase brain-derived neurotrophic factor (BDNF).

“So, there are things released from active muscles into the blood during activity that promote cell proliferation, like in the brain, with the BDNF, or stimulate or repress cancer cells.”

“During vigorous exercise our muscles essentially become mini biochemical Labs synthesizing compounds like lactate and myocin these aren't just muscle bound they get into circulation travel to far off tissues and they signal to them and they have a variety of benefits including the synthesis of elements like brain dve neurotrophic factor or bdnf crucial for brain health and neuronal health”

“it's increasing VF at the bloodb brain barrier you know staving off the breakdown of the bloodb brain barrier”

“Again, the lactate's the key. To get the lactate, you have to go harder. You have to get the vigorous intensity exercise.”

“In other words, it's a way for your muscles to communicate with other parts of your body like your brain and say, "Hey, I'm working hard here. We got to like respond to this work." Right? And part of the way that it responds is by increasing brain drive neurotrphic factor BDNF.”