Andrew Huberman· PhD
Again, one ml of topical finasteride at 0.25% leads to a 2.5mg concentration in the blood, when the effective dose within the bloodstream by taking it orally as a pill is 0.2mg.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Again, one ml of topical finasteride at 0.25% leads to a 2.5mg concentration in the blood, when the effective dose within the bloodstream by taking it orally as a pill is 0.2mg.
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for instance, taking one ml of 0.25% finasteride applied to the scalp, this is a very typical recommendation, translates to the same thing that would be achieved with 2.5mg of oral finasteride. When I say translates to the same thing, what I mean is it leads to the same concentrations in the blood.