Bryan Johnson· Author
1st Generation (Horvath, Hannum): created from data sets on people at different chronological ages (single snapshot). predicts chronological age accurately, not strongly correlated to health and longevity outcomes
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
1st Generation (Horvath, Hannum): created from data sets on people at different chronological ages (single snapshot). predicts chronological age accurately, not strongly correlated to health and longevity outcomes
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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2nd Generation (GrimAge PhenoAge): created from data on different people (single snapshot) and trained beyond predicting chronological age to predict health biomarkers and mortality risk.