Metagenomic analysis may yield false positives, and the clinical relevance of findings like Giardia or Cryptosporidium at very low abundances is not yet understood.

“it's difficult because you will find things on there that could be false positives like we were talking about a bit before uh we started recording that you know it's tricky with metagenomics you'll sometimes find things that would be worry could be worrisome like giardia at very low abundance like cryptosporidium at very very low abundance and it's we don't really yet understand at what threshold in this metagenomics that becomes clinically relevant”