Bryan Johnson· Author
Gibson 2016 found leukocyte Hsp72 mRNA needed Tcore ≥101.3°F (38.5°C) sustained for 27 min.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Gibson 2016 found leukocyte Hsp72 mRNA needed Tcore ≥101.3°F (38.5°C) sustained for 27 min.
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The lower edge sits somewhere between 101.3°F and 102.2°F (38.5 to 39°C), and it depends on the assay, exposure pattern, and cell type.
Oehler 2001 found monocyte iHsp72 needs ~102.2°F (39°C) ex vivo.