Cigarette smoke exposure initially decreases glutathione levels by 50%, which then rebound to three times basal levels within two hours and peak at 16 hours with a six-fold increase.

“long exposure and glutathione cigarette smoke exposure initially decreased that's extra extra lymphatic fluid glutathione levels is gsh by 50% but within two hours glutathione levels rebounds to three times basal level and peaked at 16 hours with a six-fold increase over repeat exposures that sounds like hormesis to me”