Inflammatory responses in the face or head area can lead to neural, meningeal, or muscular headaches.

“that inflammatory response then can trigger the pain mechanisms or what we've experience as pain mechanisms in the other three types of tissues that we talked about so for instance if you have a systemic infection or you're experiencing inflammation of any kind and it has anything to do with or encroaches on the face or head area that can easily and almost always spills over into activation of nerve cells can give rise to neural based headache or to the meninges and can give rise to meningeal headaches and of course to the muscles and to muscular type headaches”