Bryan Johnson· Author
Significant reduction of biological age across 2-4 epigenetic clocks most notably DunedinPACE, DNAmERMAge (4) and the biological age of my lungs based on organ-specific epigenetic clocks.(4)
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Significant reduction of biological age across 2-4 epigenetic clocks most notably DunedinPACE, DNAmERMAge (4) and the biological age of my lungs based on organ-specific epigenetic clocks.(4)
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Increased telomere length in circulating immune cells Ref (8), and decrease in PACE score (slowing down epigenetic aging) Ref (12)
A month into my HBOT protocol, I was encouraged to learn that the intervention scored well across several epigenetic clocks (including PACE) in the newly published research evaluating longevity interventions across all 16 epigenetic clocks. Ref (13)
Hyperbaric oxygen treatment for 3 months was able to reverse some biomarkers of aging in healthy older adults.