Paul Saladino· MD
the dead bacteria the gram-negative type specifically in its outer layer has this component called endotoxin which is really lipopolysaccharide it's actually a molecule which is a mixture of a fat and a sugar molecule right now that that molecule by itself is irritating to almost any tissue it comes in contact with including the intestinal wall now if you're depending on how much endotoxin gets produced and especially if this is done over time in other words if you're eating a lot of resistant starches which actually are resistant to the digestion absorption and they shouldn't be a lot of them will get to the column a lot of food for the bacteria very high turnover of the bacteria and if you have a lot of the ground negative species a lot of endotoxin okay over time this irritates the intestinal wall and increases its permeability