David Sinclair· PhD
New paper @Nature analyzing 11,000 profiles of cellular gene expression provides further evidence that aging is not just wear & tear but a reversible loss of epigenetic information linked directly to mortality risk
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
New paper @Nature analyzing 11,000 profiles of cellular gene expression provides further evidence that aging is not just wear & tear but a reversible loss of epigenetic information linked directly to mortality risk
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A major new paper reframes aging as a systems failure of epigenetic information. Not wear and tear but a software problem.