Cannabinoid receptors are widely distributed throughout the brain but largely absent in brainstem populations that regulate cardiac and respiratory function.

“yeah you have this very complex system and it's really widely distributed in you know it's everywhere cannaboid receptors and the endoc cannaboid molecules are in the cortex they're in the hypothalamus they're in the strum the hippocampus the cerebellum all over the except the one area where it's really interesting actually um where you don't really see much receptor is in brain stem populations that regulate um you know kind of unconscious cardiac and respiratory function”