Blindly following the protocols of anti-aging researchers like David Sinclair without considering individual factors like genetic predispositions or methylation status can be suboptimal.

“i think a lot of people would like when sinclair talks about his regimen some people might blindly assume what he's doing is optimal because he's the leading anti-aging researcher and he's at harvard and all these credentials that you're like oh my god like obviously what he does is the best thing ever on metformin he does this he does that automatically equates to i should probably do the same thing without like digging into it further not seeing genetic predispositions like the thing you mentioned with like the methylation cycle itself and having to you know deplete methyl groups and having to um assess your choline intake status you might have to supplement with betaine not getting enough creatine in”