The development of intracytoplasmic sperm injection (ICSI) in IVF has reduced the required number of sperm for conception, potentially diverting innovation and research from male fertility.

“but because it now takes just a single sperm you know through something called inid plasmic sperm injection where you can inject one egg or one sperm into an egg you know the bar has gone down dramatically you know if a couple's just trying without you know any assistance probably need 20 to 40 million moving sperm but now with you know these remarkable techniques you just need one sperm and so because of that you know I think a lot of our Innovation and research on male fertility has probably gone to the Wayside just because clinically you know we just need you know a few dozen sperm for most couples”