Andrew Huberman· PhD
MDMA massively increases serotonin & to a lesser (but still remarkable) extent, dopamine.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
MDMA massively increases serotonin & to a lesser (but still remarkable) extent, dopamine.
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the use of MDMA in the laboratory or in the clinical setting with pure MDMA has also been explored for the potential neurotoxicity of MDMA so how would methamphetamine and MDMA be neurotoxic well that's because they increase dopamine in the case of methamphetamine and dopamine and serotonin in the case of MDMA and they do so to a very high degree
the MDMA causes these massive increases in serotonin that seems to be the major source of the MDMA effect so to speak — based on the work of our colleague Rob malanka