Olfactory neurons regenerate and turn over in an activity-dependent way, requiring electrical activity dictated by smell.

“I grew up studying activity dependent wiring of the nervous system makes total sense to me why keeping neurons active keeps them alive so this is not fire together wire together type thing by the way that's a quote from Carla shats not Donal head folks or me — but this is about keeping neurons electrically active in this case Factory neurons in order to maintain their connections because otherwise they will die well all faction is a definite use it or lose it system and so that makes total sense”