David Sinclair· PhD
Life Bio is developing epigenetic reprogramming technology for liver disease, not just optic neuropathies. ER-100 will enter trials 2026, making it the first use of partial epigenetic reprogramming in humans
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Life Bio is developing epigenetic reprogramming technology for liver disease, not just optic neuropathies. ER-100 will enter trials 2026, making it the first use of partial epigenetic reprogramming in humans
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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