The mesolimbic reward pathway, involving the VTA and nucleus accumbens, is fundamentally important for desire to engage in action and is implicated in addiction.

“perhaps the most important one for today's discussion about motivation and reward is something that sometimes just called the reward pathway for the afficianados it's sometimes called the misol limic reward pathway but it's fundamentally important to your desire to engage in action and it's fundamentally important for people getting addicted to substances or behaviors”

“You have two main neural circuits in the brain that dopamine uses in order to exert all its effects. One mainly for movement, right? This is the substantia to dorsal stratum. And we've got this other pathway, the so-called misoortical liyic pathway that's for reward, reinforcement, and motivation.”