A 'k-hole' describes the subjective experience of taking ketamine at a dose that induces a pseudo-anesthetized state transitioning from sub-anesthetic to anesthetic levels.

“what is a khole in scientific terms a khole is what's used to describe the subjective experience of when somebody takes ketamine typically recreationally and they end up in basically a pseudo anesthetized state that means is that they took a dosage that for them put them beyond the boundary of the subanesthetic dose and has them transitioning into the anesthesia level dose of ketamine”