Dopamine is associated with motivation and reward-seeking behaviors, while serotonin is associated with contentment and satisfaction.

“Dopamine most commonly associated with activating neurocircuits related to motivation, craving, and reward. And Serotonin more typically activated in response to situations or conditions in which we are very happy and content with what we have. So Dopamine is more about pursuing and seeking. Serotonin is more about kind of pleasure and satisfaction with resources that we have in our immediate sphere. They don't tend to... Serotonin doesn't tend to place the brain and body into a mode of action quite as much as Dopamine does, more or less.”