Peter Attia· MD
in allergy there's no refractoriness per se if sometimes people have too much abdominal pain or they have too many hives or their asthma gets worse every time they have the dose that's where I'll say hey it might not be worth it you know this is this is just there's too many side effects here I this bothers you too much we try to decrease the dose so that we personalize it for them but some people just say this is too much now I really don't want to go through it so those people will stop doing it but in general if you stay with it you'll get the benefit from it