Paul Saladino· MD
The the concentration is all over the place. And and if the concentration is all over the place, you can't really do good studies to really know the precise dosing.
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
The the concentration is all over the place. And and if the concentration is all over the place, you can't really do good studies to really know the precise dosing.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
So you have a precise concentration. It's not all over the place, not fluctuating. Because if you just have a nasal canula, sometimes you're getting a therapeutic dose because you're breathing slow enough. Sometimes it's not therapeutic because you just took a you took a sigh or you were talking or whatever, right? The the concentration is all over the place. And and if the concentration is all over the place, you can't really do good studies to really know the precise dosing. And then how do you equate that to what we talked about earlier about how sometimes the 2% was more effective than the 4%.