Bryan Johnson· Author
The potential of stem cell derived organoids is to enable toxicity screenings for drug discovery and complex treatment regiments. This same benefit can be realized for longevity supplementation, nutrition, and Rx protocols.
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
The potential of stem cell derived organoids is to enable toxicity screenings for drug discovery and complex treatment regiments. This same benefit can be realized for longevity supplementation, nutrition, and Rx protocols.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
My organoid avatars will undertake the heavy lifting of detecting and predicting toxicity, harm, and likelihood of efficacy.
The next iteration of organoids rely on computational models, promising to evolve these systems from modeling extreme toxicity and disease states to the more delicate field of predicting chronic toxicity and harms from drugs in development.
The next iteration of organoids rely on computational models, promising to evolve these systems from modeling extreme toxicity and disease states to the more delicate field of predicting chronic toxicity and harms from drugs in development.
On the pharmaceutical side, these systems can already accelerate discovery by predicting drug candidate toxicity before they transition into expensive clinical trials. On the longevity and personal health side, this means we will soon no longer have to speculatively test interventions and therapies on ourselves based solely on general population data.
The potential of stem cell derived organoids is to enable toxicity screenings for drug discovery and complex treatment regiments. This same benefit can be realized for longevity supplementation, nutrition, and Rx protocols.