Topical finasteride application can lead to systemic blood concentrations significantly higher than the effective oral dose, potentially increasing side effect risk. — Whalespan
Topical finasteride application can lead to systemic blood concentrations significantly higher than the effective oral dose, potentially increasing side effect risk.
⚠ High risk
We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
✕NOTSUPPORTED
⚠
High-risk intervention — consult a physician before acting.Drug-drug interactions, dose-dependence, and screening contraindications apply.
“Again, one ml of topical finasteride at 0.25% leads to a 2.5mg concentration in the blood, when the effective dose within the bloodstream by taking it orally as a pill is 0.2mg. That might not seem like a big deal to you, although it is a big deal, right? We're talking 2.5mg versus 0.2, but it is a huge deal when you consider that the side effects of finasteride increase as you increase the concentration of finasteride in the bloodstream.”