Andrew Huberman· PhD
Two forms of magnesium that I'm aware of magnesium biglycinate and magnesium threonate. We believe based on the data can more actively cross the blood brain barrier.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Two forms of magnesium that I'm aware of magnesium biglycinate and magnesium threonate. We believe based on the data can more actively cross the blood brain barrier.
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Um the the main difference here and this is based on very limited amount of data. A lot of it animal data with respect to the magnesium 3 and8 is that that form of magnesium is supposed to get into and cross the bloodb brain barrier more readily and get into the brain better and then in the brain it's you know helping facilitate neurotransmission etc right helping improve cognitive function and so whereas magnesium glycinate or bislycinate you're having the magnesium attached to the glycine
So magnesium thrienate is often talked about with regard to the brain. There's one small study that suggests that maybe the thrienine attached form of magnesium helps it get across the bloodb brain barrier, but we don't know for sure.