Actively suppressing bias towards interoception or exteroception is beneficial for reducing or shifting default mode network activity.

“In both cases, whether or not you're focused on interoceptive bias or exteroceptive bias, you are going against, or I should say you're pushing back against your default mode network. I would argue it's going to be far more effective, that is, you're going to reduce or shift the activity of that default mode network far more and in a far more beneficial way if you actively try and suppress your bias toward being more interoceptive or exteroceptive.”