Andrew Huberman· PhD
concentrations of melatonin in many commercial supplements have been shown to be anywhere from 85% to 400% of what's listed on the bottle.
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
concentrations of melatonin in many commercial supplements have been shown to be anywhere from 85% to 400% of what's listed on the bottle.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
what they found is that based on what it said, on the bottle versus what was in the capsules themselves, it ranged from, I think it was 83% less than what it said on the bottle to 478% more than what it said on the bottle.
the actual amount in one pill or capsule can be off by 85% in either direction. - In either direction. Either much less than you thought or much more.
providing another reason to be conservative in their use.
can I give you two links for the show notes to uh studies of melatonin supplements that found that these melatonin supplements either had none of what they said they had in them or yes I think we wrote a newsletter on one of them oh great well there's been two
Are melatonin labels misleading?
There was like a few studies that have been published where I mean almost all these melatonin supplements that are out on the market have huge variations. Some of them have like 100 times more melatonin that's actually what's on the
But any of the larger companies, they're actually going to have pretty good quality control. And they are, if you look at those, the ones that are the bigger companies that are on the shelf, they are almost always right on target for what they should be. And I say that because what's on the bottle is actually not what's supposed to be in the bottle. And a lot of people don't know this, but the bigger companies that have the higher quality and the higher quality control are following the law. And the law says that the amount on the bottle has to be within a certain percentage of the amount that's in the pill at the