Andrew Huberman· PhD
Cade hypothesized that there's a buildup of a chemical in certain people's brains that makes them manic and they urinate that chemical out.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Cade hypothesized that there's a buildup of a chemical in certain people's brains that makes them manic and they urinate that chemical out.
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And what he did is he started to take urine from people who exhibited mania and urine from people who were not manic, and he took that urine and he would inject it into guinea pigs as an experimental model. And his general observation was that there was something in the urine that was indeed making the guinea pigs more manic if they were injected with urine from a manic patient.