Andrew Huberman· PhD
deep brain stimulation surgery but also capsulotomy which is more of an ablation approach
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
deep brain stimulation surgery but also capsulotomy which is more of an ablation approach
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
um our therapies for those patients right now uh I would say are are worth pursuing but not optimal um and so it's it's one of those things that we have to balance as a researcher because when you see patients like this you want to do everything you can to help them and I think it's important to educate patients on the risk and benefits of them this is deep brain stimulation surgery but also capsulotomy which is more of an ablation approach a little bit like deep brain stimulation but rather than delivering stimulation through an electrode you can actually heat the tissue and even destroy it.
Um there is a trial that we would like to do for OCD where we would deliver an ablation to the same area of the brain that we've been delivering ablations to for years for patients with OCD and it helps a bit. That's called a capsulotomy. Um but really the outcome is probably going to be about the same.