Peter Attia· MD
so there's association with lactate and lactic acid uh acidosis and fatigue so this whole thing was all boiled up in one knot
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
so there's association with lactate and lactic acid uh acidosis and fatigue so this whole thing was all boiled up in one knot
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And going back to the first research of Otto Meyerhof, who's one of our heroes in the study of metabolism, he had half a frog, hemicorpus, in a jar without oxygen, without perfusion, and he stimulated the muscles to contract. And as they needed energy to contract, they produced lactate. Eventually, those muscles fatigued and there was a lot of lactate. So, this is the birth of the idea that lactate causes fatigue and that lactic acidosis is a metabolic problem.