The Energy Resistance Principle states that raising glucose concentration increases energy potential, leading to increased resistance to energy flow and dissipative loss if energy is not utilized.

“If you do the we have a little equation that helps us think energetically about this called the energy resistance principle ERP and this says if you raise the concentration of glucose you raise the energy potential like the the voltage equivalent uh and then that increases energy resistance if you're not flowing that energy if you're not moving you know being active stimulated by something you just put too much food in the system it increases the the resistance to energy flow and then you start to have more dissipative loss like too much reactive oxygen species and too much you know the damage molecular damage can happen.”