The idea that high fructose corn syrup and fructose are metabolically unhealthier or more fattening per calorie than non-sugar carbohydrates is not supported by evidence when calories are controlled.

“he goes no it's really just the calories that are in it it's it's easy to overc consume consum people consume it through soda and you know they just eat too much and and the guy was like well you showed all these things in the in these mice he goes we fed them like over 50% of their calories were from Pure fructose that's pretty much impossible to get through the diet unless like you're literally doing nothing but drinking soda and he said you know we showed a pathway but that's not practical in terms of like the application to humans”