High-dose bimagrumab, used alone, increased lean mass while reducing fat, suggesting a potential role in preserving muscle and metabolic health with aging.

“Outside the combo, high-dose bimagrumab added lean mass while trimming fat, hinting at a future role in non-obese adults who want to preserve muscle and metabolic health as they age—a potential first-in-class “anabolic cardiometabolic” drug.”