Paul Saladino· MD
in people that are trying to optimize I don't think we need any of these molecules to be optimal and I think they're actually going to be a decrease because of the side effects
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We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
in people that are trying to optimize I don't think we need any of these molecules to be optimal and I think they're actually going to be a decrease because of the side effects
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
And conversely, they may have significant harm in those of you who are doing other things right, which is why I've always said, just keep it simple.