Andrew Huberman· PhD
so giving metformin kind of mimic that fasting state and reducing M productivity by drug like rapamycin also kind of mimics some aspect of the fasting state
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
so giving metformin kind of mimic that fasting state and reducing M productivity by drug like rapamycin also kind of mimics some aspect of the fasting state
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
Because metformin only inhibits mTORC1, and weaker than rapa inhibits both.
the first thing that comes to mind would be metformin