Metformin has potential benefits for dementia, cancer, and heart disease, but its effects on muscle function are not well-established and may be negative.

“it's because most clinical trials fail and most clinical trials fail because they were based on mouse data to start off with at least so maybe this is maybe this is something it's certainly worth figuring out just because the effects are so manifold you know it's it's dementia and cancer and heart disease and we don't know what else we don't know for instance what it might do to muscle function the you know the best data on that it's not good for muscle function but again that comes from early work”