Andrew Huberman· PhD
and again there's no clear explanation for it unless you believe that metformin is doing something Beyond helping you lower blood glucose
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
and again there's no clear explanation for it unless you believe that metformin is doing something Beyond helping you lower blood glucose
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
so the the study at the surface looked at people who had type 2 diabetes who were taking metformin and people who did not have type 2 diabetes and who were obviously not taking metformin and it asked the question who had a lower all cause mortality rate now of course we know that people with type 2 diabetes are going to have their lives truncated by an average of six to seven years relative to someone without type 2 diabetes so you wouldn't think that the addition of Metformin to somebody with type 2 diabetes would materially affect that maybe it would close that Gap from 6 and a half years to four years or something like that but in fact what the study found was no the the the people taking metformin with type 2 diabetes actually lived slightly longer than the people who did not in fact there was about a 15% reduction in all cause mortality over a three-year followup period obviously is done in an enormous population um using a UK um biobank um data set