Andrew Huberman· PhD
my intuition is that the metformin is helping but not helping nearly as much as we thought before
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
my intuition is that the metformin is helping but not helping nearly as much as we thought before
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
my intuition is that the metformin is helping but not helping nearly as much as we thought before
the keys paper makes it undeniably clear that in that population there was no Advantage offered by metformin that undid the disadvantage of having type 2 diabetes
the keys paper makes it undeniably clear that in that population there was no Advantage offered by metformin that undid the disadvantage of having type 2 diabetes
my intuition is that the metformin is helping but not helping nearly as much as we thought before