The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
the inhibition of pyrotechnology is not the only can cause lactate to rise just as we discussed metformin can do it but how does it do it by committing another step but still in him it's one of these steps and you're going to get a buildup of lactate because the metabolic precursions is going to build up and eventually for root will build up and that results in a beautiful lactate
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
metformin went from below one to above one in everyone who took metformin lactate you mean yes
why does lactate go up when people are taking metformin level of the liver it's in interfering uh with aerobic metabolism and so there's a block and this is very important I have erroneously always believed that so I'm really happy to be corrected I love being proved wrong I have always believed that the reason we saw an increase in fasting lactate even in healthy people if they took metformin was because of the inhibition of the ECT in skeletal muscle and you're saying not possible it can't get into skeletal muscle as absolutely not a single molecule in the world of metform has ever gotten into any skeletal muscle anywhere and tell me again why what's the transporter the organic cation transporter that's the transporter that uh by which metformin enter cells it does not exist in skeletal