Andrew Huberman· PhD
so the metformin group and 21.68 for the twin group in that's on Metformin when you adjust for age they're almost identical it's it goes from 29 point 24.93 to 24.7
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
so the metformin group and 21.68 for the twin group in that's on Metformin when you adjust for age they're almost identical it's it goes from 29 point 24.93 to 24.7
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let's just call it 17 versus 25 right 17 deaths per thousand versus 25 deaths yep and the 25 is in the folks that took metformin
there's clearly a difference here between the people who have diabetes and those who don't it complicates the study a little bit because it's basically two studies in one but you're comparing um 95 pardon me uh 24.93 to 16.86