Paul Saladino· MD
this represents a potential mechanism by which linoleic acid may be causing problems at the level of mitochondria and these inner membranes
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
this represents a potential mechanism by which linoleic acid may be causing problems at the level of mitochondria and these inner membranes
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linolic acid accumulates in your body it accumulates in all the cell membranes your mitochondrial membranes it messes up the way you make energy in your mitochondria by causing proton leak across the inner mitochondrial membrane the seed oils also can break down into harmful compounds called the Hodes and the Heats these are called ox lams or oxy liens Etc
what's the consequences of all of this linolic acid is it because it it's composition of the the cell membrane back to the mitochondrial thing we talked about with the proton leak and you know potentially impairing at a cellular energy level the hypothesis which I think is supported by the literature is that it's impairing the the biotransformation of potential energy to kinetic energy
You fill all of the membranes of your body with linoleic acid the mitochondrial membranes the cell membranes and that both creates proton leak at the mitochondria between the inner membrane and the matrix space and in the cell membrane there's there's leak of probably electrolytes sodium and potassium causing overutilization of the sodium potassium pump.
It's just it's much harder for the body to control polyunsaturated fats from an oxidative perspective than it is monounsaturated or saturated fats. And that just creates more work. And when you we know similarly to the lipopolysaccharide that when you have oxidative stress when we have reactive oxygen species that is lipid peroxides lipid peroxide radicals being formed from linoleic acid that can shut down the mitochondria too because it's a signal.